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Dernières publications
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Dylan Moutachi, Janek Hyzewicz, Pauline Roy, Mégane Lemaitre, Damien Bachasson, et al.. Treadmill running and mechanical overloading improved the strength of the plantaris muscle in the dystrophin‐desmin double knockout (DKO) mouse. The Journal of Physiology, In press, ⟨10.1113/JP286425⟩. ⟨hal-04643936⟩
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Medhi Hassani, Dylan Moutachi, Mégane Lemaitre, Alexis Boulinguiez, Denis Furling, et al.. Beneficial effects of resistance training on both mild and severe mouse dystrophic muscle function as a preclinical option for Duchenne muscular dystrophy. PLoS ONE, 2024, 19, ⟨10.1371/journal.pone.0295700⟩. ⟨hal-04501283⟩
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Antonio Atalaia, Dagmar Wandrei, Nawel Lalout, Rachel Thompson, Adrian Tassoni, et al.. EURO-NMD registry: federated FAIR infrastructure, innovative technologies and concepts of a patient-centred registry for rare neuromuscular disorders. Orphanet Journal of Rare Diseases, 2024, 19 (1), pp.66. ⟨10.1186/s13023-024-03059-3⟩. ⟨hal-04460667⟩
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Florent Porquet, Lin Weidong, Kévin Jehasse, Hélène Gazon, Maria Kondili, et al.. Specific DMPK-promoter targeting by CRISPRi reverses myotonic dystrophy type 1-associated defects in patient muscle cells. Molecular Therapy - Nucleic Acids, 2023, 32, pp.857 - 871. ⟨10.1016/j.omtn.2023.05.007⟩. ⟨hal-04287597⟩
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Caroline Le Guiner, T Larcher, A Lafoux, G Toumaniantz, S Webb, et al.. Characterization of the muscular and cardiac diseases of the DMSXL mouse model, a transgenic mouse model for Myotonic Dystrophy type 1. American Society of Gene & Cell Therapy, May 2023, LOS ANGELES, United States. ⟨hal-04096181⟩
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Dylan Moutachi, Mégane Lemaitre, Clément Delacroix, Onnik Agbulut, Denis Furling, et al.. Valproic acid reduces muscle susceptibility to contraction‐induced functional loss but increases weakness in two murine models of Duchenne muscular dystrophy. Clinical and Experimental Pharmacology and Physiology, In press, ⟨10.1111/1440-1681.13804⟩. ⟨hal-04146953⟩
Chiffres clés
144
Publications avec texte intégral
Open Access
53 %
Mots clés
Glial cells
CTG repeat contractions
Glutamate
Dilated cardiomyopathy
Acetylcholinesterase deficiency
Heart failure
Autophagy
Astrocytes
Alternative splicing
Aging
Muscular dystrophy
Myotonic Dystrophy type 1
Dystrophie Myotonique
Acute coronary syndrome
RNA interference
Cardiac muscle
CTG repeat instability
Dystrophie myotonique
Cell culture model
ARN
KNOCKOUT MICE
Gene editing
Fibrosis
CMS
Exercise
RNA biology
Dystrophin
CRISPR/Cas9
Exercice
Trinucleotide Repeat Expansion
DM1
Cultured
Antisense oligonucleotide
Hypoxia
Expression
Thérapie génique
Myotonic dystrophy
MBNL
Acetylcholinesterase knockout mouse
Trinucleotide repeat expansion
Myotonic dystrophy mouse models
Mouse model
CRISPRi
DMSXL mice
Myostatin
Myotonic dystrophy type 1
CONGENITAL MYATHENIC SYNDROME
Mice
Therapy
Genotype phenotype correlation
Motoneuron
Antisense oligonucleotides
CTG repeats
Muscle
Central nervous system
Astrocyte
PacBio
Cytoskeleton
Mouse models
Cell model
Transcriptomics
Gene therapy
Brain dysfunction
Gene Therapy
Animals
Myotonic Dystrophy Type 1
Male
Heart
Centronuclear myopathy
Oligodendrocytes
AAV
Myotonic Dystrophy
GSK3
BIOLOGIE MOLECULAIRE
Diaphragm
PCR
Transgenic mouse
Neuron
Quantitative microdialysis
Cell penetrating peptide
Endurance training
Long read sequencing
GABA
Desmin
Duchenne muscular dystrophy
Myelin
Maximal force
Humans
Oligodendrocyte
RNA splicing
Transgenic mouse model
ACETYLCHOLINESTERASE
DMPK
Intermediate filament
Skeletal muscle
Brain
Cells
Dynamin 2
Glucocorticoids
Glucocorticoid-receptor