Total synthesis of 10-norparvulenone and of O-methylasparvenone using a xanthate-mediated free radical addition - Cyclization sequence
Abstract
(Matrix presented) A short synthesis of (±)-10-norparvulenone and (±)-O-methylasparvenone was developed starting from commercially available m-methoxyphenol, hinging on a xanthate-mediated addition - cyclization sequence for the construction of the a-tetralone subunit.