A convenient metal-free reagent for the generation and capture of trifluoromethanethiol. - École polytechnique Access content directly
Journal Articles Organic Letters Year : 2013

A convenient metal-free reagent for the generation and capture of trifluoromethanethiol.

Abstract

O-Octadecyl-S-trifluorothiolcarbonate is a cheap and storable crystalline source of trifluoromethanethiol that can be prepared in two steps on a multigram scale from trifluoroacetic anhydride and sodium O-octadecyl-dithiocarbonate (xanthate). It reacts directly with gramines or with α-bromoketones and -esters in the presence of KF and pyrrolidine to give the corresponding trifluoromethyl sulfides in generally high yield.
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Dates and versions

hal-00966609 , version 1 (26-03-2014)

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Shi-Guang Li, Samir Z. Zard. A convenient metal-free reagent for the generation and capture of trifluoromethanethiol.. Organic Letters, 2013, 15 (22), pp.5898-58901. ⟨10.1021/ol403038f⟩. ⟨hal-00966609⟩
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