Passerini/Tsuji-Trost Strategy towards Pyrrole Derivatives
Résumé
The Passerini reaction of α,β‐unsaturated aldehydes affords suitable substrates for a Tsuji–Trost reaction with NH‐enamines. The latter behave as a 1,3‐bisnucleophile, which leads to the formation of pyrrole derivatives with five points of diversity through a Tsuji–Trost/Michael addition/aromatization cascade.
Origine | Fichiers produits par l'(les) auteur(s) |
---|