This text surveys cohomological properties of pairs $(U,f)$ consisting of a smooth complex quasi-projective variety $U$ together with a regular function on~it. On the one hand, one tries to mimic the case of a germ of holomorphic function in its Milnor ball and, on the other hand, one takes advantage of the algebraicity of~$U$ and $f$ to apply technique of algebraic geometry, in particular Hodge theory. The monodromy properties are expressed by means of tools provided by the theory of linear differential equations, by mimicking the Stokes phenomenon. In the case of tame functions on smooth affine varieties, which is an algebraic analogue of that of a holomorphic function with an isolated critical point, the theory simplifies much and the formulation of the results are nicer. Examples of such tame functions are exhibited.