A convergent route to functional protected amines, diamines, and β-amino acids
Abstract
Phthalimide protected amines react with NBS under peroxide initiation to give geminal phthalimido-bromo derivatives, which are readily converted into the corresponding xanthates. These xanthates in turn undergo radical additions to numerous olefins, providing a convergent and modular access to densely functionalized protected amines and diamines.