Discovery of a Novel and Selective Indoleamine 2,3-Dioxygenase (IDO-1) Inhibitor 3-(5-Fluoro-1 H -indol-3-yl)pyrrolidine-2,5-dione (EOS200271/PF-06840003) and Its Characterization as a Potential Clinical Candidate - École polytechnique Access content directly
Journal Articles Journal of Medicinal Chemistry Year : 2017

Discovery of a Novel and Selective Indoleamine 2,3-Dioxygenase (IDO-1) Inhibitor 3-(5-Fluoro-1 H -indol-3-yl)pyrrolidine-2,5-dione (EOS200271/PF-06840003) and Its Characterization as a Potential Clinical Candidate

Stefano Crosignani
  • Function : Correspondent author
  • PersonId : 1030353

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Patrick Bingham
  • Function : Author
Deepak Dalvie
  • Function : Author
Jun Li Feng
  • Function : Author
Bruno Gomes
  • Function : Author
Samantha Greasley
  • Function : Author
Stephen Kaiser
  • Function : Author
Manfred Kraus
  • Function : Author
Karen Maegley
  • Function : Author
Nichol Miller
  • Function : Author
Brion Murray
  • Function : Author
James Soloweij
  • Function : Author
Albert Stewart
  • Function : Author
Joseph Tumang
  • Function : Author
Vince Torti
  • Function : Author
Martin Wythes
  • Function : Correspondent author
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Dates and versions

hal-01760561 , version 1 (06-04-2018)

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Stefano Crosignani, Patrick Bingham, Pauline Bottemanne, Hélène Cannelle, Sandra Cauwenberghs, et al.. Discovery of a Novel and Selective Indoleamine 2,3-Dioxygenase (IDO-1) Inhibitor 3-(5-Fluoro-1 H -indol-3-yl)pyrrolidine-2,5-dione (EOS200271/PF-06840003) and Its Characterization as a Potential Clinical Candidate. Journal of Medicinal Chemistry, 2017, 60 (23), pp.9617 - 9629. ⟨10.1021/acs.jmedchem.7b00974⟩. ⟨hal-01760561⟩
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